Cai Zhao

Research Assistant Professor
School of Medicine
广东省深圳市南山区学苑大道1088号南方科技大学
caiz@mail.sustech.edu.cn

SELF-INTRODUCTION:

Research focuses include multi-omics analysis of clinical microbiome and air microbiome. Research outcomes have been published in international journals including Journal of Antimicrobial Chemotherapy,Applied and Environmental Microbiology、Computational and Structural Biotechnology Journal,American Journal of Respiratory and Critical Care Medicine etc.

 

EDUCATION:

2012/8-2017/2, Ph.D, Singapore Centeron Environmental and Life Sciences Engineering, Nanyang Technological University, Singapore

2008/8-2012/5, B.Eng, School of Chemical and Biomedical Engineering, Nanyang Technological University, Singapore

 

WOKRING EXPERIENCE:

2020/5- Current, Research Assistant Professor, School of Medicine, Southern University of Science and Technology

2020/3-2020/4, Research Fellow, School of Medicine, Southern University of Science and Technology

2017/4-2020/2, Research Fellow, Singapore Centeron Environmental and Life Sciences Engineering, Nanyang Technological University, Singapore           

 

PUBLICATIONS:

1. Peiyan Zhang#,Zhao Cai#,Weibo Wu,Ling Peng,Yinfeng Li,Chuming Chen,Li Chen,Jianming Li,Mengli Cao,Shiyan Feng,Xiao Jiang, Jing Yuan, Yingxia Liu, Liang Yang†, Fuxiang Wang† The novel coronavirus (COVID-19) pneumonia with negative detection of viral ribonucleic acid from nasopharyngeal swabs: A case report,BMC Infectious Diseases, DOI : 10.1186/s12879-020-05045-z

2. Zhenpeng Li#, Zhao Cai#, Zeqiong Cai, Yanhong Zhang, Tongtong Fu, Yongxin Jin, Zhihui Cheng, Shouguang Ji, Weihui Wu, Liang Yang†, Fang Bai† (2020) Extensively Drug-Resistant Molecular Genetic Analysis of An XDR-Pseudomonas aeruginosa ST664 Clone Carrying Multiple Conjugal Plasmids, Journal of Antimicrobial Chemotherapy

3. Tingting Wang#, Zhao Cai#, Xiaolong Shao, Weitong Zhang, Yingpeng Xie, Yingchao Zhang, Canfeng Hua, Stephan C. Schuster, Liang Yang, Xin Deng (2019) The Pleiotropic Effects of c-di-GMP Content in Pseudomonas syringae, Applied and Environmental Microbiology. 2019 Mar 8. pii: AEM.00152-19. doi: 10.1128/AEM.00152-19

4. Zhao Cai#, Yang Liu#, Yicai Chen, Joey Kuok Hoong Yam, Su Chuen Chew, Song Lin Chua, Ke Wang, Michael Givskov and Liang Yang (2015) RpoN Regulates Virulence Factors of Pseudomonas aeruginosa via Modulating the PqsR Quorum Sensing Regulator, International journal of molecular sciences, 2015, 16, 28311–28319

5. Fang Bai#, Zhao Cai#, Liang Yang (2019) Recent progress in experimental and human disease-associated multi-species biofilms, Review, Computational and Structural Biotechnology Journal, 2019, 17, 1234-1244

6. Micheál Mac Aogáin#, Kenny J. X. Lau#, Cai Zhao, Jayanth Kumar Narayana, Rikky W.Purbojati, Daniela I. Drautz-Moses, Nicolas E. Gaultier, Tavleen K. Jaggi, Pei Yee Tiew,

Thun How Ong, Mariko Siyue Koh, Albert Lim Yick Hou, John A. Abisheganaden, Krasimira Tsaneva-Atanasova, Stephan C. Schuster, Sanjay H. Chotirmall. (2020) Metagenomics Reveals a Core Macrolide Resistome Related to Microbiota in Chronic Respiratory Disease, American Journal of Respiratory and Critical Care Medicine, doi: 10.1164/rccm.201911-2202OC. [Epub ahead of print]

7. Yaqin Song, Chun Yang, Gukui Chen, Yixi Zhang, Zijing Seng, Zhao Cai, Chao Zhang, Liang Yang, Jianhua Gan, and Haihua Liang (2019) Molecular insights into the master regulator CysB mediated bacterial virulence in Pseudomonas aeruginosa. Molecular Micorbiology, doi: 10.1111/mmi.14200

8. Yingying Cheng, Joey Kuok Hoong Yam, Zhao Cai, Yichen Ding, Lian-Hui Zhang, Yinyue

Deng, Liang Yang (2018) Population dynamics and transcriptomic responses of Pseudomonas aeruginosa in a complex laboratory microbial community, npj Biofilms and Microbiomes doi: 10.1038/s41522-018-0076-z

9. Lin Chua S, Liu Y, Li Y, Jun Ting H, Kohli GS, Cai Z, Suwanchaikasem P, Kau Kit Goh K,Pin Ng S, Tolker-Nielsen T, Yang L, Givskov M. (2017) Reduced Intracellular c-di-GMP Content Increases Expression of Quorum Sensing-Regulated Genes in Pseudomonas aeruginosa. Front Cell Infect Microbiol. 2017 Oct;7:451. doi: 10.3389/fcimb.2017.00451

10. Song Lin Chua, Yichen Ding, Yang Liu, Zhao Cai, Jianuan Zhou, Sanjay Swarup, Daniela I.Drautz-Moses, Stephan Christoph Schuster, Staffan Kjelleberg, Michael Givskov and Liang Yang (2016) Reactive oxygen species drive evolution of pro-biofilm variants in pathogens by modulating cyclic-di-GMP levels; Open Biology, 6: 160162

11. Victor Bochuan Wang, Song-Lin Chua, Zhao Cai, Krishnakumar Sivakumar, Qichun Zhang,Staffan Kjelleberg, Bin Cao, Say Chye Joachim Loo, Liang Yang (2014) A stable synergistic microbial consortium for simultaneous azo dye removal and bioelectricity generation; Bioresource Technology, 155 (2014) 71–76

12. Yang-Chun Yong, Zhao Cai, Yang-Yang Yu, Peng Chen , Rongrong Jiang , Bin Cao , Jian-Zhong Sun, Jing-Yuan Wang, Hao Song (2013) Increase of riboflavin biosynthesis underlies enhancement of extracellular electron transfer of Shewanella in alkaline microbial fuel cells; Bioresource Technology, 130 (2013) 763–768

13. Yang-Chun Yong, Jing-Xian Wang, Zhao Cai and Jian-Zhong Sun. (2013) Chapter 5 Quorum sensing for clean environment and green bioenergy. Advances in Environmental Research. Volume 28. pp. 129-148. ISBN: 978-1-62417-738-5.(Book chapter)